Benzalkonium chloride (BAK) is a common preservative in topical ocular preparations; however, prolonged use may lead to deleterious effects on the ocular surface, affecting the quality of life and reducing adherence to treatment and overall outcomes. A Recent study in India compared the intraocular pressure (IOP)-lowering efficacy and safety of a novel once-daily, BAK-free, a fixed-dose combination of latanoprost plus timolol with latanoprost or timolol administered as monotherapy or concomitantly.
The fixed dose combination is used to reduce intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) and ocular hypertension (OHT) who are insufficiently responsive to topical beta-blockers or prostaglandin analogues. Latanoprost works by increasing the outflow of aqueous fluid from the eyes through the uveal-scleral tract and timolol is beta blocker that decreases the…
