With increasing armamentarium of glucose lowering drugs, it has become critical for physicians to decide their prescription composition with anti-diabetic medication. For this indirect or head-to-head comparative discussion on existing classes of anti-diabetics are very important. This article provides a comparative discussion on SGLT-2 inhibitor class of medication with few other existing anti-diabetics. Metformin is recommended as the first-line therapy for ages in almost every diabetes treatment guidelines.
However, a significant number of patients cannot tolerate the biguanide because of its gastrointestinal side effects or for other contraindications to its use. Which drug to be prescribed to those patients or to those not well controlled with metformin monotherapy is still a debatable topic. A new class of glucose-lowering therapies is emerging with the recent advent of three…
