Spot the name of the protein from the grid using the following hints: This protein maintains telomere length in dividing cells. This protein is associated with the treatment of neurodegenerative diseases. Its absence increases ROS generation and causes oxidative damage in neurons. Click here for the correct answer! Explanation: Telomerase reverse transcriptase (TERT) protein ameliorates the effects of pathological proteins associated with neurodegeneration, such as tau, amyloid-β, and α-synuclein, thereby combating age-related cognitive decline and various other aspects of neurodegenerative diseases.
Reference: Spilsbury A, Miwa S, Attems J, Saretzki G. The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro. J Neurosci. 2015 Jan 28;35(4):1659-74. Did you find this activity interesting?
