Wholehearted Laughter increases Interleukin 12b, which In turn activates  NK CELLS natural killer cells  — which kill cancer cells and viruses like Corona. A Japanese Study. A Japanese Research On effects of Wholehearted laughter — 4 weeks study on effects of Comedy shows and laughter revealed this - Rise in interleukin 12b.,and Increased efficacy in killing  Neoplastic cells and viruses.

Laughter Reduces Cortisol levels — Enhances Immunity. With the mechanism described above.