Although the PSA screening has caused 50% mortality reduction due to prostate cancer, it also results in overdiagnosis and overtreatment. The 4Kscore is a blood test that accurately determines the risk of aggressive prostate cancer and reduces prostate biopsies by 65%. Regular PSA Screening Typically, prostate cancer is suspected following routine screening with a prostate-specific antigen (PSA) blood test and/or digital rectal examination. In either case, abnormal findings typically result in a prostate biopsy.
It is estimated that approximately 700,000 to 1 million prostate biopsies are performed annually. However, a majority of these biopsies discover no cancer (approximately 50% of all biopsies performed) or an indolent, non-life-threatening, Gleason score 6 cancer (approximately 25% of all biopsies performed). The disadvantage of PSA testing is that a number of men undergo…
