Case presentation A 66-year-old male with a known history of coronary artery disease and valvular heart disease, with valve replacement done 19 years ago, developed carcinoma of the breast. In addition, he had comorbidities of non-insulin-dependent diabetes mellitus (NIDDM). Medical history He was planned for surgery, which was dropped after he developed a stroke two days before the surgery. He was given anastrozole 1 mg/day as he was positive for estrogen and progesterone receptors on the tumor. He did well for 18 months until chest wall nodules reappeared.

He received radiotherapy to the chest wall, to which he responded well for 22 months. After that, the chest wall nodules reappeared, which gradually increased and ulcerated. No other treatment was offered other than 2nd and 3rd line hormonal therapy (tamoxifen and letrozole), which did not benefit him much. He was presented with…