A 29-year-old woman suffering from cervical adenopathy, weight loss, and night sweats. Lymph node biopsy analysis- CD30+, CD2+, CD3-, CD4+, anaplastic lymphoma kinase (ALK)-positive anaplastic large-cell lymphoma. Staging evaluations - adenopathy in the mediastinum and retroperitoneum PMH reveals no evidence of bone marrow disease.
LDH is twice the upper limit of normal and ECOG performance status is 1. What could be the most appropriate initial therapy for this patient? *This case is from Docplexus Editorial Team for educative purpose only.
