Continuous renal replacement therapy (CRRT) is a therapeutic process that involves a dialysis machine with a dialyzer, to continuously clean a patient’s blood for an extended period, without stopping. Hemodialysis therapy in critically ill pediatric patients requires much more monitoring and care, especially due to their fragile conditions, including low birth weight. Furthermore, the hemofiltration machines used for adult patients are difficult to use in neonates and pediatric patients. To address this unmet need, the U.S.

FDA has recently granted permission for the marketing of a novel CRRT device for use in critically ill pediatric patients weighing between 2.5 and 10 kilograms (or 5.5 to 22 pounds). Introduction : Globally, around 1,00,000 children with acute kidney injury have a minimal survival rate. These pediatric patients need dialysis to survive. The novel CRRT machine is the…