A Child With A Growing Nodule On The Tongue

A 7-year-old boy was presented to the clinic with complaints of multiple, firm, painless, slow-growing nodules on the tongue for the last 3 years. Additionally, the child had a history of mild developmental delay. Physical Examination High arched palate Marfanoid habitus Laboratory Findings Calcitonin: 407 ng/L Serum metanephrines: within physiological limits Biopsy of the tongue Presence of mucosal neuromas Radiological Examination Ultrasonography of the neck showed hypoechoic thyroid nodules without the presence of cervical lymphadenopathy Genetic Analysis The patient was found to have a mutation of the RET proto-oncogene.

What is the most likely diagnosis for the patient? Option A: Gaucher’s Disease Option B: Multiple Endocrine Neoplasia Type 2B Option C: Marfan’s Syndrome *The patient case is from Docplexus editorial team for educative purpose only. Source: The New England Journal…