Acute generalized exanthematous pustulosis (AGEP) is an acute drug eruption characterized by erythematous plaques and papules studded with numerous, pinpoint pustules. Several atypical clinical presentations and triggers of AGEP have been described in the literature. This article describes the effective approaches to early identification and intervention of AGEP. Cutaneous adverse reactions to drugs are common and encompass a variety of mild to severe and life-threatening reactions.
AGEP is a severe cutaneous adverse reaction characterized by the rapid development of non-follicular, sterile pustules on an erythematous base. Although many causative factors leading to AGEP have been described, antibiotics are the most common cause of AGEP. Aminopenicillins, sulphonamides, quinolones, hydroxychloroquine, terbinafine, and diltiazem are the most frequent causative drugs. In particular cases,…
