Synopsis During nephrectomy, an enormous strain is placed on homeostatic mechanisms which regulate intravascular volume and blood pressure due to preoperative fasting and anesthesia. When coupled with intraoperative fluid losses and diminished cardiac output, this can significantly reduce kidney perfusion and subsequently lead to acute kidney injury (AKI). The present study investigates whether preoperative dehydration and intraoperative hypotension were associated with postoperative acute kidney injury in patients managed surgically for kidney tumors. This week’s “ MED FACT ” discusses a retrospective observational study from International Urology and Nephrology, “ Association between preoperative hydration status and acute kidney injury in patients managed surgically for kidney tumors ”.
Authors: RJ. Ellis et. al. Key Takeaways Preoperative dehydration may be associated with…