Acute pancreatitis is inflammatory process in which pancreatic enzymes autodigest the gland, with high morbidity and 10 to 15% mortality even in this modern treatment era. Pancrease is exo and endocrine gland, by weight 80% exocrine and 20 %endocrine, in this acute pancreatitis only exocrine part play the role, by activation of trypsin and breaking of zymogen granule mechnism this inflammatory process started. Etiology of acute pancreatitis may be like this: Biliary cause : Gall stone sliped from bile duct to ampulla of vater and obstruct the pancreatic flow responsible for40% cases and most common in eastern world.
Alcohol is responsible 35% of cases in western world with ald alcoholic liver diseases. Post ERCP 4% Trauma for 1.5% cases either stab wound or blunt injury on abdomen more common in children. Drugs: many drugs like sulfa, tetracycline, furosemide, azathioprine and valproic…
