Salient Features: Fully vaccinated people remain at risk for SARS-CoV-2 infections and the same can be serious and fatal at times. 35% patients hospitalized with COVID-19 in Massachusetts were fully vaccinated. In the event of infection viral load is the same in vaccinated and unvaccinated patients. However, the viral load decline faster in vaccinated patients and they are less likely to transmit infection.
In UK study fully vaccinated people (n = 55 962)were two-thirds less likely to harbor SARS-CoV-2 compared with unvaccinated people (n = 15 135), with absolute rates of 0.40% vs 1.21%,respectively. In a study of 7771 household contacts of 4921 index cases in the Netherlands, the rate of transmission from fully vaccinated household members was 13% vs 22% (Vaccine Efficacy for preventing transmission 63% }. The rate of hospitalization among US adults was 83.6 per 100000 in unvaccinated…
