Bio-integrative implants have been proposed to offer potential advantages, including lower removal rates and enhanced bone interaction, supported by biomechanical and histological evidence; however, robust clinical data remain scarce. To address this gap, a randomized clinical trial evaluated whether bio-integrative screws could achieve non-inferior healing and complication outcomes compared with metallic screws in 24 patients undergoing calcaneal osteotomies. With a median follow-up of 2 years, the study found that bone healing rates were similar at 6 weeks (83.3% vs 66.7%), 12 weeks (100% vs 91.7%), and 96 weeks (100% vs 100%).
Minor complication rates were identical (16.7% vs 16.7%) and patient-reported outcomes did not differ significantly, with no major complications or secondary surgeries observed in either group. These findings suggest that bio-integrative screws provide…
