One of the organ malignancies for which serum tumor markers can help in disease management is testicular cancer. Human chorionic gonadotropin, alpha-fetoprotein, and lactate dehydrogenase play vital roles in germ cell tumors. This article discusses the clinical applications of testicular cell tumor markers, along with some additional serum molecules that have been identified with potential roles as germ cell tumor markers.
Testicular cancer represents approximately 1% of all cancers diagnosed in men and is the most common solid organ malignancy among men aged 15–35 years. Testicular germ cell tumors (GCTs) are unique in that tumor markers are readily available to guide clinicians in disease management. Testicular cancer tumor markers Alpha-fetoprotein (AFP) It’s a 70 kilodalton single-chain glycoprotein, synthesized in the yolk sac, liver, and intestine that serves as a major serum…
