Several observational studies have suggested earlier that prolonged blood storage may be associated with an increased risk of cardiovascular events. However, the most definitive evidence to date again claims that mortality rates don't differ for a patient receiving a fresh blood transfusion as compare to oldest blood. Randomized, controlled trials have suggested that prolonged storage of blood does not increase the risk of adverse outcomes among patients after transfusion.
But, most of these trials were restricted to high-risk populations and were not powered to detect small but clinically significant differences in mortality. However, the mortality rate after transfusion in a general population of hospitalized patient was yet to be assessed. Recent Study and Outcome A new data came from the Informing Fresh versus Old Red Cell Management (INFORM) based on pragmatic, randomized,…
