Synopsis Despite the lack of evidence-based clinical efficacy data, high-flow nasal cannula oxygen therapy has emerged as a recent method of treating bronchiolitis in infants. Furthermore, the efficacy of such high-flow oxygen therapy is not well established in settings other than intensive care units (ICUs). This week’s “ MED FACT ” discusses a randomized, multi-center, controlled trial from the New England Journal of Medicine, ‘ A Randomized Trial of High-Flow Oxygen Therapy in Infants with Bronchiolitis ’ , March 2018.

Authors : Franklin D, Babl F E, Schlapbach L J , et al. Key Takeaways Early initiation of high-flow oxygen therapy in infants with bronchiolitis results in a significantly reduced rate of escalation of care when compared to that of standard oxygen therapy. Objective: To assess if early initiation of high-flow nasal cannula oxygen therapy in infants with bronchiolitis…