Synopsis Meconium aspiration syndrome (MAS) is one of the most common causes of morbidity in neonates. Infants born with meconium staining of amniotic fluid (MSAF) are 100-fold more likely to develop substantial respiratory distress than infants born through clear amniotic fluid. However, there is little evidence on type of respiratory support to be provided to such patients. This week’s “ MED FACT ” discusses a randomized, parallel group trial from JAMA Pediatrics, “ Effect of Nasal Continuous Positive Airway Pressure on Infants With Meconium Aspiration Syndrome: A Randomized Clinical Trial ”, 2018. Authors: A. Pandita, S.

Murki, T. P. Oleti, et al. Key Takeaways The use of Bubble Nasal Continuous Positive Airway Pressure (NCPAP) reduces the need for mechanical ventilation in the first 7 days of life in infants with MAS. Objective: To compare NCPAP with standard care in neonates with…