Globally, at least, 7.6 million children are born annually with severe genetic or congenital anomalies. In a country with a diverse socioeconomic background like in India, precise prevalence data are difficult to collect and in most cases they remain undiagnosed. The genetic and congenital abnormality is the second most common cause of infant and childhood mortality and occurs with a prevalence of 25- 60 per 1000 births. There are several factors that lead to a higher chance of genetic abnormality in children.
Such factors include The tradition of consanguineous marriage, which results in a higher rate of autosomal recessive conditions including congenital malformations, stillbirths, or mental retardation. Furthermore, maternal age greater than 35 years is associated with higher frequencies of chromosomal abnormalities in the offspring. Genetic diseases can vary in severity, from being…
