CABG Outperforms Stents in Women with Chronic Coronary Disease

Women account for only 20% to 25% of participants in chronic coronary artery disease (CAD) trials, limiting clear comparisons between percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG). To address this gap, researchers evaluated long-term outcomes of PCI versus CABG in women with chronic CAD using real-world data (n = 4,066; mean age, 66.5 years). Over a median follow-up of 5.1 years, PCI was associated with a higher risk of major adverse cardiovascular and cerebrovascular events (MACCE; hazard ratio [HR]: 1.81) and all-cause mortality (HR: 1.34) compared with CABG.

Cardiovascular readmissions for myocardial infarction, heart failure, or stroke were also more frequent after PCI than CABG (HR: 1.40). Overall, these findings suggest that CABG provides superior long-term outcomes in women with chronic CAD by reducing MACCE and all-cause mortality compared…