CABG Reduces Mortality Compared To PCI With Drug Eluting Stents

CABG better than PCI with drug-eluting stents for multivessel CAD Coronary artery bypass grafting (CABG) offered a significantly reduced risk of all-cause death, myocardial infarction (MI), and stroke in patients with left main or multivessel coronary artery disease (CAD) when compared with percutaneous coronary intervention (PCI) with drug-eluting stents (DES). Why this matters? Despite advances in the surgical and percutaneous treatment of left main or multivessel CAD, which treatment works best remains controversial. Study design Patient-level meta-analysis of 3 randomized trials comparing CABG vs PCI with DES.1639 patients underwent CABG and 1641 underwent PCI with DES.

Median follow-up 5 years. Key results A lower rate of all-cause death, MI, or stroke in CABG group than PCI with DES (13.0% vs 16.0%; P=.046), mainly due to lower rates of MI. CABG benefits significant in patients…