Diabetes -related pathways, including changes in hyperinsulinemia/insulin-like growth factor axis, fat-induced inflammation, and sex hormone levels, have been proposed to initiate breast cancer (BCa). 1,2 However, limited research has been conducted on the association between type 1 ( T1D ) and 2 (T2D) diabetes and the risk of developing BCa. Now, a study analyzed the data of 250,312 women aged 40 to 69 years to determine the relationship between diabetes and BCa risk. 3 In the study, while 575 women had T1D and 7,891 women had T2D at baseline, 6,821 women developed T2D over 11.1 years.
A total of 383 diabetic women and 7,745 non-diabetic women were diagnosed with BCa during the study duration . However, researchers found no overall association between diabetes and BCa risk. Further, women with T1D were found to have a higher risk of BCa (adjusted hazard ratio, aHR = 1.52) compared to…
