The current article summarizes newly discovered as well as conventional markers that could be predictive in cardiac surgery. The NIH definition : The biomarker is a characteristic that is objectively measured and evaluated as an indicator of normal biological processes, pathogenic processes, or pharmacologic responses to therapeutic intervention. Biomarkers involved in cardiac surgery are unique and diverse tools that: enable the surgeon to manage the treatment process facilitate the follow-up process after surgery gives insight regarding myocardial function . Hence, until 1970s lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) were used widely.
Afterward, cardiac creatine kinase (CK-MB) was accepted by surgeons. After that, during 2000s cardiac troponin T (cTnT) was the specific biomarker for myocardial function. However, recently new markers have been presented that could…
