Synopsis Early-stage pediatric Hodgkin Lymphoma (HL) is considered as a curable disease. Previously, children with HL, treated with radiotherapy alone was enough. As time progressed treatment with combined modality therapy (CMT) with chemotherapy and radiotherapy have shown to result in greater event-free survival (EFS) rates and overall survival (OS) rates, but with radiotherapy, significant toxic effects were observed during follow-ups.
So, in this study, the intent was to identify the various positive and negative effects of combined modality therapy (CMT) in comparison to chemotherapy alone on a patient’s overall health and survival rate. The present study analyses the use of radiotherapy within the CMT regimen and their outcomes compared with chemotherapy alone in early-stage pediatric Hodgkin Lymphoma. This Journal Watch discusses the clinical trial from Journal of Jama Oncology,…
