Thyrotoxicosis refers to the hypermetabolic clinical syndrome resulting from serum elevations in thyroid hormone levels, specifically free thyroxine and/or triiodothyronine. Several effective forms of therapy for thyrotoxicosis exist, all of which have advantages and disadvantages. This article briefly discusses the controversies in the thyrotoxicosis treatment. Thyrotoxicosis occurs in approximately 2% of women and 0.2% of men.

Thyrotoxicosis due to Graves' disease most commonly develops between the second and fourth decades of life, whereas the prevalence of toxic nodular goiter increases with age. Autoimmune forms of thyrotoxicosis are more prevalent among smokers. Current Controversies in management of Thyrotoxicosis Establishing Etiology It is important to establish the etiology of thyrotoxicosis before its management. Several clinical studies have reported hyperthyroidism from…