In a disturbing development, at least 14 children in Madhya Pradesh have died following suspected kidney failure linked to a toxic cough syrup — Coldrif, manufactured by Sresan Pharmaceuticals, Kancheepuram, Tamil Nadu. The syrup was found to contain diethylene glycol (DEG) at levels far exceeding permissible limits. DEG is a dangerous solvent known to cause acute renal toxicity and death. For doctors, awareness of the implicated manufacturer is crucial to avoid similar tragedies.
Following reports of adverse events, Tamil Nadu drug control authorities tested Coldrif and published their findings on October 2. The sample (Batch No: SR‑13; Manufactured: May 2025; Expiry: April 2027) was declared adulterated, containing 48.6% w/v diethylene glycol — a toxic level with severe health implications. In response, Tamil Nadu banned the sale of Coldrif on Friday, ahead of further state and…
