A 71-year-old man presented to the emergency department with complaints of worsening dyspnea. The patient had a history of renal cell carcinoma and was treated with pazopanib as the first line metastasis treatment. He reported symptomatic bilateral lung metastasis and multiple subpleural lesions three months ago, and was receiving cabozantinib 60 mg oral daily doses. A CT scan revealed a volumetric reduction of the lung nodules along with the onset of an apical grade 3 pneumothorax on the left side. In your opinion, what would be the cause of pneumothorax? Option A. Progression of the lung metastases. Option B.
Rapid and significant shrinkage of lung lesions. Option C. Spontaneous rupture of air blisters. Option D. Cabozantinib induced severe interstitial lung disease. Stay tuned for the correct answer! This image challenge is from the editorial team of Docplexus and is meant for…