Patient History: The patient was a 64-year-old man with chronic lymphocytic leukemia, which required treatment with chemotherapy and allogeneic umbilical cord blood transplantation. He was also on multiple drugs, in particular, systemic prednisone and tacrolimus. Ten months after the transplantation, the patient developed a slow-growing pruriginous lesion on the right leg. Physical Examination: Examination revealed a well-defined and painless tumor-like lesion on the right leg measuring 4cm, with the secretion of a hemoserous discharge through several holes (Fig. 1).
No granules were observed in the discharge. Histopathology: Histological study revealed an intense mixed inflammatory and granulomatous infiltrate in the dermis, several abscesses, and multinucleated Langerhans giant cells and foreign body giant cells (Figs. 2A and 2B). PAS staining highlighted thick-walled septate…
