Neuromyelitis optica (NMO) or Devic’s disease is a rare inflammatory and demyelinating autoimmune disorder of the central nervous system. It is characterized by recurrent attacks of optic neuritis (ON) and longitudinally extensive transverse myelitis (LETM), which is distinct from multiple sclerosis (MS). The present article is extracted from the original source ‘EFNS guidelines on diagnosis and management of neuromyelitis optica’, published in European Journal of Neurology (PDF File Attached for Detailed Reference).

Diagnostic Recommendations: The predominant course is characterized by recurrent severe attacks of myelitis and/or uni- or bilateral ON with incomplete recovery and is up to 10 times more prevalent in women than in men. Clinical features to diagnose Neuromyelitis optica: Optic neuritis: The occurrence of bilateral simultaneous ON or sequential ON in rapid succession is…