The 2026 update to the Early Detection of Prostate Cancer Guideline has been jointly issued by the American Urological Association (AUA) and the Society of Urologic Oncology (SUO). This update is intended for clinicians involved in the care of individuals with a prostate gland, including urologists, oncologists, and primary care providers engaged in prostate cancer screening and diagnosis. Developed through a systematic review of contemporary evidence (November 2022 to December 2024), the guideline aims to provide a structured, evidence-based framework for early detection of prostate cancer.
It focuses on optimizing clinical decision-making across key domains, including PSA-based screening, imaging (particularly MRI), biomarker utilization, and biopsy strategies. The overarching goal is to improve detection of clinically significant prostate cancer while minimizing overdiagnosis and…
