Synopsis The recent study gives a clinical evidence of the fact that copeptine based measurement of Diabetes Insipidus (DI) has a greater clinical significance in terms of diagnostic accuracy than the conventional age-old water deprivation test. This week's ' MED FACT ' discusses a clinical trial from Endocrine Research, “ A Copeptin-Based Approach in the Diagnosis of Diabetes Insipidus (DI) ”. 2018. Authors : W. Fenske, J.

Refardt, I. Chifu, et.al. Key Takeaways The key takeaways from the research finding can be divided into 2 parts:  First being, that copeptin can be better molecule for the diagnosis of diabetes insipidus from the long-proven method of indirect water deprivation. And secondly, being that copeptine has a differential diagnostic value to diagnose between primary DI and central DI, unlike that of desmopressin which is used to a similar effect but for the differential…