Food protein–induced enterocolitis syndrome (FPIES) is defined as a non-IgE cell mediated severe form of food allergy that may further lead to shock . It typically presents in infancy, with repetitive protracted vomiting that begins approximately 1 to 4 hours after food ingestion. The current article describes the differential diagnosis of FPIES.
Clinical presentation Mild-to-moderate acute FPIES : The clinical features of mild-to moderate acute FPIES includes vomiting (onset usually 1-4 h, can range from 30 min to 6 h), few episodes of intermittent vomiting can be bilious, decreased activity level, pallor, and presence of occasional mild watery diarrhea. Severe acute FPIES: The clinical presentation includes projectile, repetitive vomiting (onset usually at 1-4 h, can range from 30 min to 6 h, altered behavior ranging from decreased activity to lethargy, pallor, dehydration, requires…
