Transdermal estrogen therapy delivered through the skin moderately improved sexual function in early postmenopausal women reported a clinical study published in the JAMA Internal Medicine. The clinical study examined changes in sexual function in 670 post-menopausal women. They were randomized to receive either oral conjugated equine estrogens (o-CEE), transdermal 17β-estradiol (t-E2) or placebo. The study reported that the transdermal treatment was associated with moderate improvement in the overall sexual function score when compared with placebo.
Source: Taylor, Hugh S., et al. "Effects of Oral vs Transdermal Estrogen Therapy on Sexual Function in Early Postmenopause: Ancillary Study of the Kronos Early Estrogen Prevention Study (KEEPS)." JAMA internal medicine 177.10 (2017): 1471-1479. According to you, do estrogen therapies improve overall sexual function in early post-menopause?
