Night shift work is known to increase the risk of obesity and coronary heart disease and to adversely affect healthy aging. A recent study examined whether night shift work is also associated with osteoporosis and osteoporosis-related fractures among 276,774 individuals aged 40–69 years. The study showed that individuals engaged in usual or permanent night shift work had a significantly higher risk of osteoporosis (hazard ratio [HR] 1.29).
Higher odds were also observed among those with ≥10 years of night shift exposure (odds ratio [OR] 1.21) and those working 3–8 night shifts per month. These associations remained robust after adjustment for chronic diseases, cancer, sleep duration, outdoor activity, supplement use, female-specific factors, and genetic susceptibility. Night shift work was additionally associated with an increased risk of osteoporosis-related pathological fractures (HR…
