Tooth extraction is associated with various adverse outcomes (AO). These AO include pain, bleeding, swelling, trismus, delayed healing and infection. Furthermore; extraction of tooth results in bone resorption causing recession around adjacent teeth thus hindering the functional and aesthetic implant and prosthetic rehabilitation. Autologous Platelet Concentrates (APCs) provide an opportunity to reduce some of these negative effects.
The most popular APC modalities include Platelet Rich Plasma (PRP), Platelet Rich Fibrin (PRF) and Platelet Rich in Growth Factor (PRGF) . High concentrations of platelets have shown to play an important role in tissue healing, and growth factors regulated cellular events such as cell migration, proliferation, and differentiation, in addition to the synthesis of the extracellular matrix. A systematic review and meta-analysis regarding the use of APCs…
