Synopsis The risk of recurrent stroke ranges from 3 to 15% in the first 3 months after a minor ischemic stroke or a transient ischemic attack (TIA). The present study aims to evaluate the efficacy of dual antiplatelet therapy after a minor ischemic stroke or TIA. This week’s “ MED FACT ” discusses a clinical trial from The New England Journal of Medicine, “Clopidogrel and Aspirin in Acute Ischemic Stroke and High-Risk TIA”. Authors: S. Claiborne Johnston et.
al. Key Takeaways Combination antiplatelet therapy with clopidogrel and aspirin may reduce the rate of recurrent stroke during the first 3 months after a minor ischemic stroke or TIA but may impose a higher risk of major hemorrhage than aspirin alone. Objective: To evaluate antiplatelet efficacy of combination, clopidogrel plus aspirin in comparison with aspirin alone, in minor ischemic stroke or TIA. Study Type: Randomized,…
