Highlights Hyaluronic acid (HA) plays an important role in corneal epithelial wound healing through mechanisms including cell migration, proliferation, and tissue repair ¹. In a study using in vivo corneal debridement model, HA-containing artificial tears permitted the initial process of corneal wound healing , with the HPG/HA formulation showing the highest proportion of complete re-epithelialization at 24 hours compared with other HA containing artificial tear products tested.¹ The average area and percentage area of re-epithelialization were higher with HPG/HA ( Systane Hydration ) compared with other HA-containing formulations¹.
In in vitro models of human corneal epithelium , HA/HPG formulations demonstrated greater protection against desiccation, improved epithelial barrier protection, and reduced surface friction compared with single-polymer formulations ². These experimental…
