Highlights • Artificial tears improve symptoms of dry eye disease. ¹, ² • Combination formulations are more effective than single active ingredient artificial tears. ² • PEG containing artificial tears are more effective than those containing carboxymethylcellulose and hydroxypropyl methylcellulose² • Symptomatic benefit is typically observed within approximately one month of regular use (about four times daily).
² Artificial tears remain the cornerstone of therapy in Dry Eye Disease (DED) and have been found to reduce symptoms and signs of dry eye disease. 1,2 Modern formulations employ sodium hyaluronate (HA), polyethylene glycol (PEG), propylene glycol (PG), carboxymethylcellulose (CMC), and hydroxypropyl guar (HP-Guar) to target specific tear-film layers and parameters such as NIBUT, TMH, and ocular-surface staining. 1,2 The transition from single-agent lubricants to multi-polymer…
