Infants and young children with a family history of atopy are at high risk of developing allergic disease, and those with a personal history of atopy, particularly those with moderate-to-severe eczema, are also at increased risk of developing other atopic diseases including food allergies. The American Academy of Pediatrics (AAP) had previously suggested in 2000 that the introduction of certain highly allergenic foods be delayed further in high-risk children: cow's milk (CM) until age one year; eggs until age two years; and peanuts, tree nuts, and fish until age three years.
However, this advisory was modified in 2008 with the consensus that there was insufficient evidence to recommend any specific practices concerning the introduction of these foods after four to six months for the prevention of allergic disease in high-risk infants. Four recent randomized trials have examined the…