Early versus Delayed umbilical cord clamping has been a debatable topic in the gynecology fraternity, as there are various complimentary opinions about this procedure. Although current guidelines approve this procedure, several concerns revolve around its safety and benefits. In this regard, a recent review investigated the effects of delayed versus early cord clamping on hospital mortality (primary outcome) and morbidity in preterm infants.
Randomized clinical trials (RCTs) of delayed (≥ 30 seconds) vs early (<30 seconds) clamping in infants born <37 weeks gestation were selected. Furthermore, relative risk (i.e. Risk Ratio, RR), risk difference (RD) and mean difference (MD) with 95% confidence intervals (CI) were assessed by fixed effects models, heterogeneity by I2 statistics and the quality of evidence by Grading of Recommendations Assessment, Development, and Evaluation (GRADE).…
