Etoricoxib is generally available in 30mg, 60mg, 90mg, and 120mg dose of oral formulation. Our earlier post had highlighted that a twice daily dose of etoricoxib 90mg (Click For Insights) has the potential of causing Toxic epidermal Necrolysis (TEN). The present study highlights cases were etoricoxib, even at a dose of 60mg caused severe dermatological presentation. Cases of TEN Induction With Etoricoxib (60mg) Case 1: Age & Associated Disease: 59-year-old man administered etoricoxib at a dose of 60 mg⁄day for osteoarthritis and fever.
Nikolsky Sign: Positive Management Of Case 1: Injecting augmentin 1.2 g intravenously twice a day + metronidazole 100 ml thrice a day. Parenteral dexamethasone 8 mg administered intravenously twice a day was given for 7 days. Pentoxifylline 400 mg was prescribed twice a day along with silver sulfadiazine 1% and chlorhexadine gluconate 0.2%…
