Highlights Evidence suggests that a combination of acetylsalicylic acid and warfarin does more harm than good by increasing bleeding events. Reducing the use of acetylsalicylic acid reduced the bleeding outcomes. Deprescription of acetylsalicylic acid improved clinical outcomes for patients receiving warfarin and serves as a model for health systems. Acetylsalicylic acid is frequently prescribed for the prevention of primary coronary artery disease and secondary stroke in cardiovascular patients who have cardiovascular disease or had a history of ischemic attack.

Acetylsalicylic acid is combined with warfarin in patients with atrial fibrillation or venous thromboembolism post-acute coronary syndromes or percutaneous coronary interventions. Do the benefits outweigh the risks? Know the findings of a 2022 study, β€œ Assessment of an Intervention to Reduce Aspirin Prescription for patients…