Millions of people worldwide are blind due to corneal disease or damage. Corneal transplantation and Descemet’s stripping endothelial keratoplasty (DSEK) have demonstrated good results. However, shortage of cornea donors limits the success of these treatments. In addition, the successful transplantation of human corneal grafts depends on the immune responses of the body.
Development of artificial corneas is a promising alternative to obtaining corneal transplants. A research team has shown that artificial corneas can be an effective option for patients blind due to corneal diseases. In this study, researchers developed a novel scaffold that was derived from fish scales, as a functional material for corneal regenerative applications. For this study, fish scales were acellularized, decalcified and fabricated into collagen scaffolds, such that these processes did not affect the three…
