Evans L. et al. have published international guidelines to manage sepsis and septic shock in adult patients. The guidelines have been divided into five categories. 1 Among them, best practice management and strong recommendations were published in Part 1 of this post .
Guidelines on weak recommendations, insufficient evidence, and no recommendation are provided in this article. Weak Recommendations Weak recommendations to manage sepsis or septic shock patients were made based on the low- and very low-quality evidence from the previous studies. Evaluate blood lactate for the patients with suspected sepsis. Administer intravenous (IV) crystalloid fluid (30 mL/Kg) within three hours of resuscitation for patients with septic shock or sepsis-mediated hypoperfusion. Use dynamic measures ( Explanation box 1 ) to guide fluid resuscitation instead of static parameters and physical examination…
