Resting heart rate has been validated as a prognostic marker in many diseases including hypertension, coronary artery disease, and heart failure (HF). Heart rate influences all the progressive stages of cardiovascular events, from an initial epithelial dysfunction that proceeds via atherosclerotic lesion and plague formation to end stage cardiovascular disease. Studies have indicated the inverse relationship between resting heart rate and mortality in general population as well as in patients having cardiovascular diseases.
Heart rate has been implicated as an influential factor at all stages of a progressive heart disease and thus, it has evolved as a prognostic marker and target for treatment of chronic cardiac failure. Prospective studies carried out in healthy population reflected that an increased resting heart rate might predispose to obesity and diabetes mellitus by development…
