Kaposi sarcoma (KS) is aggressive cancer caused by human herpesvirus-8, primarily seen in immunocompromised patients. It is rarely reported before death as most patients with hepatic KS do not manifest symptoms or evidence of liver injury. Patients with clinically significant hepatic injury due to hepatic KS usually have an aggressive course of disease with hepatic failure often progressing to multi-organ failure and death. This article provides an insight of this medical entity.
Hepatic Kaposi sarcoma (KS) is a clinical presentation that disproportionately affects the human immunodeficiency virus/acquired immune deficiency syndrome (AIDS) population. KS is an angioproliferative low-grade neoplasm that is associated with human herpesvirus-8 (HHV-8). The iatrogenic form is due to HHV-8 activation caused by medical immunosuppression from treatment of autoimmune disorders or post-organ…