Clinicians, patients, their families, and regulators must all understand the difference between treatments that are potentially curative and the majority that are palliative. Based on risks, benefits, and possibilities, the patient gives informed consent for an intervention. Any guidance offered by the drug industry warrants investigation of patient-level information, as conducted by the Nordic Cochrane Collaboration and the all trials initiative. Some clinicians, unaware of the machinations of the drug industry, feel empowered, even invincible when they follow clinical practice guidelines and standard of care recommendations that have been sanctioned by the state.
They assume that they are underpinned by science. Other doctors, aware that the goal of several drug industries is to market their drugs, review both positive and negative data and apply clinical judgment . There are no…