Vitamin D deficiency has been linked to a higher risk of respiratory tract infections (RTI), but evidence across different ethnic groups remains limited. To address this gap, a study examined the association between serum 25-hydroxyvitamin D levels and hospitalization for respiratory tract infections involving 36,258 participants. The study found that higher serum 25-hydroxyvitamin D levels were associated with a lower risk of hospitalization for respiratory tract infections, with each 10 nmol/L increase linked to a 4% reduction in risk (hazard ratio (HR) 0.96).

Participants with severe vitamin D deficiency (<15 nmol/L) had a significantly higher risk of RTI hospitalization compared with those with levels ≥75 nmol/L (HR 1.33), while intermediate categories showed no significant associations. The findings were consistent across regression models, with no significant interaction observed…