The human serum contains a physiological plethora of bioactive elements which are naturally released by activated platelets and might have a significant effect on the regeneration of corneal layers by stimulating the cell growth. This mechanism supported the use of human serum eye drops in some ocular diseases associated with dystrophic changes and alterations of the tear film, such as persistent corneal epithelial defects and dry eye syndrome. Cornea, composed of collagen and water is enveloped by epithelium and endothelium layers which cooperate to ensure tissue homeostasis by providing adequate corneal transparency and reliability.
Prior injury, corneal epithelial cells regenerate and restore the physiologic tissue architecture. In addition, a concomitant nerve regrowth and a controlled neovascularization of the damaged surface may occur. Cellular loss needs replacement by cell…
