Approximately 50% of all cancer patients are treated with radiotherapy. Radiation therapy has become an integral part of modern treatment strategies but it is associated with some life-threatening effects. To improve radiotherapy, hyperthermia attributed as a potent sensitizer. Today, Dr. Nagraj G. Huilgol, the world-renowned Radiation Oncologist, Haldar Memorial Oration, IMA’s Citation & Life Time Awardee throws light on “Hyperthermia for Cancer Management”. Interviewer: Hello Dr.

Nagraj, can you shed some light into the physiological effects of hyperthermia? Dr Nagraj: Hyperthermia is raising intratumoral temperature to 41-450C. This is quite different from HIFU or RF ablation. All the chemical processes are temperature dependent. Thus, raising intratumoral temperature alters the functions of the cell membrane, cytosolic organelle, and vascular perfusion. Hyperthermia is…